TARGETING TREATMENT RESISTANCE: UNVEILING THE POTENTIAL OF RNA METHYLATION REGULATORS AND TG-101,209 IN PAN-CANCER NEOADJUVANT THERAPY

Targeting treatment resistance: unveiling the potential of RNA methylation regulators and TG-101,209 in pan-cancer neoadjuvant therapy

Abstract Background Tumor recurrence and mortality rates remain challenging in cancer patients despite comprehensive treatment.Neoadjuvant chemotherapy and immunotherapy aim to eliminate residual tumor cells, reducing the risk of recurrence.However, drug resistance during neoadjuvant therapy is a significant hurdle.Recent studies suggest a correlat

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The Response of Composite Ecosystem Services to Urbanization: From the Perspective of Spatial Relevance and Spatial Spillover

Ecosystems offer a wide array of benefits to support human livelihoods and enhance the quality of life.Quantitative evaluation of ecosystem services (ESs) is crucial for achieving the goal of sustainable development.The Yellow River Basin has a large population, and there are contradictions and conflicts in ecological protection, resource utilizati

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